MYCOPLASMA PNEUMONIA IN CHILDREN CAUSED BYMYCOPLASMA PNEUMONIAE

Abstract

Mycoplasma pneumoniae, an obligate parasitic pathogen without a cell wall that can cause severe upper and lower respiratory tract symptoms. It is the causative agent of bronchitis and pneumonia in humans. In addition to severe respiratory symptoms, after infection with M. pneumoniae, clinical extrapulmonary manifestations from the skin, brain, kidneys, musculoskeletal system, digestive system and even the circulatory system are observed. Intrapulmonary and extrapulmonary pathogenetic mechanisms of M.pneumoniae infection are independent and interrelated, and also have certain common features. In fact, the pathogenetic mechanisms of M. pneumoniae are complex, and the specific content is still not fully clear, further studies are needed to determine the detailed pathogenesis of M. pneumoniae. This review article describes data on the effects of M. pneumoniae on bronchial epithelial cells and respiratory tract in children.