IMMUNOLOGICAL ASPECTS OF THE CYTOMEGALOVIRUS INFECTIONS AFTER PEDIATRIC LIVER TRANSPLANTATION
Abstract
The cytomegalovirus (CMV) is one of the most frequent virus agents having an influence on the results of hepatic transplantation. The cytomegalovirus (CMV) is widespread both among the patients in the condition of long-term medicamentous prophylactic suppression and among the population in general (60-100%). It is the main risk that can cause the loss of the transplant and the death of the patient after fulfillment of the hepatic transplantation. Decrease in the quantity of similar complications by means of various methods of prevention was demonstrated in the two meta-researches. According to the information received, HCMV develops within the first year after hepatic transplantation fulfillment without use of preventive antiviral preparations approximately in 44–65% of the cases.
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