SYNTHESIS OF FUNCTIONALLY SUBSTITUTED CYCLOPANCARBOXYLIC ACIDS: IN SILICO STUDY OF THEIR INHIBITORY INFLUENCE ON ETHYLENE BIOSYNTHESIS

Abstract

Ethylene, a critical plant hormone, plays a vital role in various physiological processes within plants. To comprehend its impact on growth, senescence delay, and postharvest quality, researchers use ethylene biosynthesis inhibitors. These inhibitors, including structural analogs of ACC (1-aminocyclopropane-1-carboxylic acid), effectively suppress ethylene production. In this study, we investigate the docking interaction between 1-chloro-2-hexyl-cyclopropane-1-carboxylic acid and ACC oxidase through in silico experiments using cheminformatic methods. Our synthesized compounds demonstrate advantages over existing ethylene inhibitors, holding promise for future applications in agriculture.